Assay Detail
Binding
CHEMBL5554697
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human IDO1 using tryptophan as substrate assessed as reduction in N-formylkynurenine formation preincubated with compound for 5 mins followed by tryptophan addition and measured after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752711 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752711 | — | IC50 | = | 60.0 | nM | 7.22 |