Assay Detail
Functional
CHEMBL5577119
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Antiproliferative activity against human NCI-H295R cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H295R |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioisosteric heterocyclic analogues of natural bioactive flavonoids by scaffold-hopping approaches: State-of-the-art and perspectives in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.00 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3623611 | — | — | 1 | 8.30 |
| CHEMBL393477 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3623611 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL393477 | — | IC50 | = | 20.0 | nM | 7.70 |