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Assay Detail

CHEMBL5577924

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Binding
Binding affinity to C5a (unknown origin) assessed as dissociation constant incubated for 1 hr by CD analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Complement C5 (CHEMBL2364163)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure of Designer Antibody-like Peptides Binding to the Human C5a with Potential to Modulate the C5a Receptor Signaling.
Ghosh M, Gupta PK, Behera LM, Rana S.
J Med Chem (2024) 67 : 14110 -14124
PubMed 39051153 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 6.10 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5594178 1 6.16
CHEMBL5594087 1 6.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5594178 Kd = 700.0 nM 6.16
CHEMBL5594087 Kd = 940.0 nM 6.03