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Assay Detail

CHEMBL5579062

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-cancer activity against human MOLT-4 cells incubated for 72 hrs by Cell Titer Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLT-4
Confidence 1 — Organism
Curated By Autocuration

Target

MOLT-4 (CHEMBL614177)
Type CELL-LINE
Organism Homo sapiens

Publication

Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities.
Deb R, Torres MDT, Boudný M, Koběrská M, Cappiello F, Popper M, Dvořáková Bendová K, Drabinová M, Hanáčková A, Jeannot K, Petřík M, Mangoni ML, Balíková Novotná G, Mráz M, de la Fuente-Nunez C, Vácha R.
J Med Chem (2024) 67 : 14040 -14061
PubMed 39116273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5594579 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5594579 IC50 = 1000.0 nM 6.00