Assay Detail
Binding
CHEMBL5579238
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to BRD9 (unknown origin) by TR-FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.22 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5591100 | — | — | 1 | 8.30 |
| CHEMBL3823478 | — | — | 1 | 8.14 |
| CHEMBL1957266 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5591100 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL3823478 | — | IC50 | = | 7.2 | nM | 8.14 |
| CHEMBL1957266 | — | IC50 | > | 10000.0 | nM | - |