Assay Detail
Binding
CHEMBL5579290
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H](2S, 4R)-4-MeGlu (SYM-2081) from GluK2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutamate receptor ionotropic, kainate 2 (CHEMBL3683) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1232313 | DOMOIC ACID | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1232313 | DOMOIC ACID | Ki | = | 6.04 | nM | 8.22 |