Assay Detail
Functional
CHEMBL5579422
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Antiviral activity against influenza A virus H1N1 A/Puerto Rico/8/1934 infected in MDCK cells assessed as reduction in viral proliferation incubated for 24 hrs by FFU assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.62 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5583722 | — | — | 1 | 6.82 |
| CHEMBL5591147 | — | — | 1 | 6.53 |
| CHEMBL5589992 | — | — | 1 | 6.51 |
| CHEMBL5583748 | — | — | 1 | - |
| CHEMBL5583975 | — | — | 1 | - |
| CHEMBL5595779 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5583722 | — | EC50 | = | 152.0 | nM | 6.82 |
| CHEMBL5591147 | — | EC50 | = | 297.0 | nM | 6.53 |
| CHEMBL5589992 | — | EC50 | = | 307.0 | nM | 6.51 |
| CHEMBL5583748 | — | EC50 | - | — | - | |
| CHEMBL5583975 | — | EC50 | - | — | - | |
| CHEMBL5595779 | — | EC50 | - | — | - |