Assay Detail
Functional
CHEMBL5579641
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Antiviral activity against pseudotyped Sudan ebolavirus Gulu infected in human A549 cells assessed as inhibition of viral growth
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sudan ebolavirus |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.02 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5584196 | — | — | 1 | 6.26 |
| CHEMBL5593153 | — | — | 1 | 6.19 |
| CHEMBL5589828 | — | — | 1 | 6.11 |
| CHEMBL5595489 | — | — | 1 | 6.08 |
| CHEMBL5591525 | — | — | 1 | 6.05 |
| CHEMBL5594836 | — | — | 1 | 6.00 |
| CHEMBL5583881 | — | — | 1 | 5.98 |
| CHEMBL5591328 | — | — | 1 | 5.91 |
| CHEMBL5593953 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5584196 | — | EC50 | = | 554.0 | nM | 6.26 |
| CHEMBL5593153 | — | EC50 | = | 641.0 | nM | 6.19 |
| CHEMBL5589828 | — | EC50 | = | 771.0 | nM | 6.11 |
| CHEMBL5595489 | — | EC50 | = | 834.0 | nM | 6.08 |
| CHEMBL5591525 | — | EC50 | = | 884.0 | nM | 6.05 |
| CHEMBL5594836 | — | EC50 | = | 1010.0 | nM | 6.00 |
| CHEMBL5583881 | — | EC50 | = | 1040.0 | nM | 5.98 |
| CHEMBL5591328 | — | EC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL5593953 | — | EC50 | = | 2390.0 | nM | 5.62 |