Assay Detail
Functional
CHEMBL5579643
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against pseudotyped Tai Forest ebolavirus infected in human A549 cells assessed as inhibition of viral growth
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Tai Forest ebolavirus |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 5.42 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5589828 | — | — | 1 | 5.77 |
| CHEMBL5584196 | — | — | 1 | 5.57 |
| CHEMBL5595489 | — | — | 1 | 5.43 |
| CHEMBL5594836 | — | — | 1 | 5.38 |
| CHEMBL5583881 | — | — | 1 | 5.37 |
| CHEMBL5591525 | — | — | 1 | 5.30 |
| CHEMBL5591328 | — | — | 1 | 5.28 |
| CHEMBL5593153 | — | — | 1 | 5.25 |
| CHEMBL5593953 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5589828 | — | EC50 | = | 1690.0 | nM | 5.77 |
| CHEMBL5584196 | — | EC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL5595489 | — | EC50 | = | 3740.0 | nM | 5.43 |
| CHEMBL5594836 | — | EC50 | = | 4140.0 | nM | 5.38 |
| CHEMBL5583881 | — | EC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL5591525 | — | EC50 | = | 4950.0 | nM | 5.30 |
| CHEMBL5591328 | — | EC50 | = | 5280.0 | nM | 5.28 |
| CHEMBL5593153 | — | EC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL5593953 | — | EC50 | > | 100000.0 | nM | - |