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Assay Detail

CHEMBL5579981

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Functional
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Natural products fragment-based design and synthesis of a novel pentacyclic ring system as potential MAPK inhibitor.
Hou BL, Wu K, Liu R, Liu J, Wang J, Wang C, Liang Y, Wang Z.
Bioorg Med Chem Lett (2024) 99 : 129598 -129598
PubMed 38169246 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5590126 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5590126 IC50 = 250.0 nM 6.60