Assay Detail
Binding
CHEMBL5580335
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC6 (unknown origin) using fluorophore tripeptide substrate preincubated for 10 mins followed by substrate addition and measured for 30 mins by microtiter plate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Re-exploration of tetrahydro-β-carboline scaffold: Discovery of selective histone deacetylase 6 inhibitors with neurite outgrowth-promoting and neuroprotective activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.33 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2364628 | RICOLINOSTAT | 2.0 | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2364628 | RICOLINOSTAT | IC50 | = | 4.7 | nM | 8.33 |