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Assay Detail

CHEMBL5580468

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human SW620 cells assessed as reduction in cell growth incubated for 96 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SW-620
Confidence 1 — Organism
Curated By Autocuration

Target

SW-620 (CHEMBL612262)
Type CELL-LINE
Organism Homo sapiens

Publication

2-(3-Indolyl)acetamides and their oxazoline analogues: Anticancer SAR study.
Aksenov DA, Smith JL, Aksenov AV, Prityko LA, Aksenov NA, Kuzminov IK, Aleksandrova EV, Sathish P, Mesa-Diaz N, Vernaza A, Zhang A, Du L, Kornienko A.
Bioorg Med Chem Lett (2024) 102 : 129681 -129681
PubMed 38432288 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.02 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5594478 1 6.43
CHEMBL5596005 1 5.85
CHEMBL5595121 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5594478 IC50 = 370.0 nM 6.43
CHEMBL5596005 IC50 = 1410.0 nM 5.85
CHEMBL5595121 IC50 = 1710.0 nM 5.77