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Assay Detail

CHEMBL5580662

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Dual-target inhibitors of colchicine binding site for cancer treatment.
Lu L, Li K, Pu J, Wang S, Liang T, Wang J.
Eur J Med Chem (2024) 274 : 116543 -116543
PubMed 38823265 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.29 5.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5190121 1 5.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5190121 IC50 = 5160.0 nM 5.29