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Assay Detail

CHEMBL5580799

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CDK1 (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 1 (CHEMBL308)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity.
Huang Y, Liu W, Zhao C, Shi X, Zhao Q, Jia J, Wang A.
Eur J Med Chem (2024) 275 : 116547 -116547
PubMed 38852339 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.33 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5280928 1 7.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5280928 Ki = 46.8 nM 7.33