Assay Detail
Binding
CHEMBL5580804
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Inhibition of CDK9 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.60 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5499697 | — | — | 1 | 8.70 |
| CHEMBL5592751 | — | — | 1 | 8.10 |
| CHEMBL4555799 | — | — | 1 | 7.64 |
| CHEMBL3673434 | — | — | 1 | 7.54 |
| CHEMBL4582951 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5499697 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5592751 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4555799 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL3673434 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL4582951 | — | IC50 | = | 910.0 | nM | 6.04 |