Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5580922

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human C-33-A cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type C-33-A
Confidence 1 — Organism
Curated By Autocuration

Target

C-33-A (CHEMBL2366313)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel Hsp90-Targeting PROTACs: Enhanced synergy with cisplatin in combination therapy of cervical cancer.
Liang J, Wang D, Zhao Y, Wu Y, Liu X, Xin L, Dai J, Ren H, Zhou HB, Cai H, Dong C.
Eur J Med Chem (2024) 275 : 116572 -116572
PubMed 38861809 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5590945 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5590945 IC50 = 70.0 nM 7.16