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Assay Detail

CHEMBL5581278

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activation of Myosin S1 ATPase activity in bovine Cardio-myofibril
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The U.S. FDA approved cardiovascular drugs from 2011 to 2023: A medicinal chemistry perspective.
Jiang Y, Liu P, Qiu Z, Zhou M, Cheng M, Yang T.
Eur J Med Chem (2024) 275 : 116593 -116593
PubMed 38889609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4297517 MAVACAMTEN 4.0 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4297517 MAVACAMTEN IC50 = 300.0 nM 6.52