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Assay Detail

CHEMBL5582387

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 5HT2A (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design and Evaluation of 3-Phenyloxetane Derivative Agonists of the Glucagon-Like Peptide-1 Receptor.
Zhang Z, Pan H, Guo L, Cai C, Chen T, Zhang Z, Yang X, Zheng H, Jiang C, Wang Z, Yang Y, Wang Z, Zhang X, Zhang Y, Liu D.
J Med Chem (2024) 67 : 14820 -14839
PubMed 39140772 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.06 5.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5590455 1 5.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5590455 IC50 = 8757.0 nM 5.06