Assay Detail
Binding
CHEMBL5582399
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to full length His-tagged human PP5 extracted from Escherichia coli BL21 assessed as dissociation constant by ITC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein phosphatase 5 (CHEMBL3425389) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Allosteric Activation of Protein Phosphatase 5 with Small Molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.94 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5593159 | — | — | 1 | 5.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5593159 | — | Kd | = | 1140.0 | nM | 5.94 |