Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5582681

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human U373 MG cells assessed as reduction in cell growth incubated for 72 hrs by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U-373MG ATCC
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Cellular, Structural Basis, and Recent Progress for Targeting Murine Double Minute X (MDMX) in Tumors.
Yin Q, Hu Y, Dong Z, Lu J, Wang H.
J Med Chem (2024) 67 : 14723 -14741
PubMed 39185935 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5267044 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5267044 IC50 = 1000.0 nM 6.00