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Assay Detail

CHEMBL5584769

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of ADP-induced platelet aggregation in New Zealand White rabbit
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Oryctolagus cuniculus
Cell Type Platelet
Confidence 1 — Organism
Curated By Autocuration

Target

Platelet (CHEMBL4296519)
Type CELL-LINE

Publication

Research progress of prodrugs for the treatment of cerebral ischemia.
Zheng H, Wu H, Wang D, Wang S, Ji D, Liu X, Gao G, Su X, Zhang Y, Ling Y.
Eur J Med Chem (2024) 272 : 116457 -116457
PubMed 38704941 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.53 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5596213 1 7.00
CHEMBL833 TICLOPIDINE 4.0 1 6.44
CHEMBL249818 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5596213 IC50 = 100.0 nM 7.00
CHEMBL833 TICLOPIDINE IC50 = 360.0 nM 6.44
CHEMBL249818 IC50 = 700.0 nM 6.16