Assay Detail
Functional
CHEMBL5584808
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Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in c-Met-based dual inhibitors in the treatment of cancers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.96 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5598465 | — | — | 1 | 5.43 |
| CHEMBL5596467 | — | — | 1 | 5.10 |
| CHEMBL5597950 | — | — | 1 | 4.92 |
| CHEMBL5596177 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5598465 | — | IC50 | = | 3710.0 | nM | 5.43 |
| CHEMBL5596467 | — | IC50 | = | 7930.0 | nM | 5.10 |
| CHEMBL5597950 | — | IC50 | = | 12130.0 | nM | 4.92 |
| CHEMBL5596177 | — | IC50 | = | 43000.0 | nM | 4.37 |