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Assay Detail

CHEMBL5584831

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Functional
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances in c-Met-based dual inhibitors in the treatment of cancers.
Jin F, Lin Y, Yuan W, Wu S, Yang M, Ding S, Liu J, Chen Y.
Eur J Med Chem (2024) 272 : 116477 -116477
PubMed 38733884 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.83 5.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5597495 1 5.83

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5597495 IC50 = 1463.0 nM 5.83