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Assay Detail

CHEMBL5584912

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH radical scavenging activity incubated for 30 mins
10
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.
Mughal EU, Hawsawi MB, Naeem N, Hassan A, Alluhaibi MS, Ali Shah SW, Nazir Y, Sadiq A, Alrafai HA, Ahmed SA.
Eur J Med Chem (2024) 273 : 116523 -116523
PubMed 38795518 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 10 6.07 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5598380 1 6.20
CHEMBL196 ASCORBIC ACID 4.0 1 6.19
CHEMBL5597242 2 6.16
CHEMBL5598085 1 6.09
CHEMBL5598195 1 6.02
CHEMBL5596796 1 6.01
CHEMBL5596056 1 5.98
CHEMBL5597315 1 5.96
CHEMBL5590860 1 5.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5598380 IC50 = 633.0 nM 6.20
CHEMBL196 ASCORBIC ACID IC50 = 640.0 nM 6.19
CHEMBL5597242 IC50 = 691.0 nM 6.16
CHEMBL5597242 IC50 = 690.0 nM 6.16
CHEMBL5598085 IC50 = 814.0 nM 6.09
CHEMBL5598195 IC50 = 950.0 nM 6.02
CHEMBL5596796 IC50 = 983.0 nM 6.01
CHEMBL5596056 IC50 = 1052.0 nM 5.98
CHEMBL5597315 IC50 = 1098.0 nM 5.96
CHEMBL5590860 IC50 = 1322.0 nM 5.88