Assay Detail
Functional
CHEMBL5584913
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Antioxidant activity assessed as ABTS radical scavenging activity
10
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.76 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5597242 | — | — | 2 | 7.70 |
| CHEMBL153 | TROLOX | — | 1 | 7.55 |
| CHEMBL5598380 | — | — | 1 | 6.78 |
| CHEMBL5596056 | — | — | 1 | 6.67 |
| CHEMBL5590860 | — | — | 1 | 6.34 |
| CHEMBL5597315 | — | — | 1 | 6.29 |
| CHEMBL5598195 | — | — | 1 | 6.25 |
| CHEMBL5598085 | — | — | 1 | 6.20 |
| CHEMBL5596796 | — | — | 1 | 6.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5597242 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5597242 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL153 | TROLOX | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL5598380 | — | IC50 | = | 167.0 | nM | 6.78 |
| CHEMBL5596056 | — | IC50 | = | 216.0 | nM | 6.67 |
| CHEMBL5590860 | — | IC50 | = | 461.0 | nM | 6.34 |
| CHEMBL5597315 | — | IC50 | = | 519.0 | nM | 6.29 |
| CHEMBL5598195 | — | IC50 | = | 562.0 | nM | 6.25 |
| CHEMBL5598085 | — | IC50 | = | 629.0 | nM | 6.20 |
| CHEMBL5596796 | — | IC50 | = | 712.0 | nM | 6.15 |