Assay Detail
Binding
CHEMBL5584914
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Inhibition of alpha-glucosidase (unknown origin)
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.29 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5598380 | — | — | 1 | 6.75 |
| CHEMBL5598085 | — | — | 1 | 6.66 |
| CHEMBL5597242 | — | — | 1 | 6.60 |
| CHEMBL5590860 | — | — | 1 | 6.54 |
| CHEMBL5597315 | — | — | 1 | 6.43 |
| CHEMBL5596796 | — | — | 1 | 6.42 |
| CHEMBL5598195 | — | — | 1 | 6.34 |
| CHEMBL5596056 | — | — | 1 | 6.33 |
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5598380 | — | IC50 | = | 176.0 | nM | 6.75 |
| CHEMBL5598085 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL5597242 | — | IC50 | = | 251.0 | nM | 6.60 |
| CHEMBL5590860 | — | IC50 | = | 291.0 | nM | 6.54 |
| CHEMBL5597315 | — | IC50 | = | 367.0 | nM | 6.43 |
| CHEMBL5596796 | — | IC50 | = | 384.0 | nM | 6.42 |
| CHEMBL5598195 | — | IC50 | = | 457.0 | nM | 6.34 |
| CHEMBL5596056 | — | IC50 | = | 473.0 | nM | 6.33 |
| CHEMBL404271 | ACARBOSE | IC50 | = | 28690.0 | nM | 4.54 |