Assay Detail
Functional
CHEMBL5585018
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Antiproliferative activity against human CAL-51 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAL-51 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hijacking monopolar spindle 1 (MPS1) for various cancer types by small molecular inhibitors: Deep insights from a decade of research and patents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.15 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5598395 | — | — | 1 | 8.00 |
| CHEMBL4585148 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5598395 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4585148 | — | IC50 | = | 500.0 | nM | 6.30 |