Assay Detail
Functional
CHEMBL5585108
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Antiproliferative activity against human OCI-AML2 cells assessed as reduction in cell viability
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OCI-AML2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules that regulate the N<sup>6</sup>-methyladenosine RNA modification as potential anti-cancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.85 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | 3.0 | 1 | 7.00 |
| CHEMBL38434 | BREQUINAR | 2.0 | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL38434 | BREQUINAR | IC50 | = | 200.0 | nM | 6.70 |