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Assay Detail

CHEMBL5585124

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Research progress on GPX4 targeted compounds.
Li B, Cheng K, Wang T, Peng X, Xu P, Liu G, Xue D, Jiao N, Wang C.
Eur J Med Chem (2024) 274 : 116548 -116548
PubMed 38838547 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1951048 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1951048 IC50 = 21.0 nM 7.68