Assay Detail
Functional
CHEMBL5585129
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human A549 cells xenografted in mouse assessed as tumor growth inhibition at 5 mg/ml,ip administrated for 21 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Research progress on GPX4 targeted compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.38 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463064 | BUFOTALIN | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463064 | BUFOTALIN | IC50 | = | 4210.0 | nM | 5.38 |