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Assay Detail

CHEMBL5585765

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against mouse C8D1A cells incubated for 3 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type C8-D1A
Confidence 1 — Organism
Curated By Autocuration

Target

C8-D1A (CHEMBL5209892)
Type CELL-LINE
Organism Mus musculus

Publication

5-HT<sub>6</sub> receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives.
Drop M, Koczurkiewicz-Adamczyk P, Bento O, Pietruś W, Satała G, Blicharz-Futera K, Canale V, Grychowska K, Bantreil X, Pękala E, Kurczab R, Bojarski AJ, Chaumont-Dubel S, Marin P, Lamaty F, Zajdel P.
Eur J Med Chem (2024) 275 : 116615 -116615
PubMed 38936149 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.43 4.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5598162 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5598162 IC50 = 37400.0 nM 4.43