Assay Detail
Binding
CHEMBL5586202
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Inhibition of Plasmodium falciparum DHFR N51I/C59R/S108N/I164L quadruple mutant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel flexible biphenyl <i>Pf</i>DHFR inhibitors with improved antimalarial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.27 | 9.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3040038 | — | — | 1 | 9.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3040038 | — | Ki | = | 0.54 | nM | 9.27 |