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Assay Detail

CHEMBL5586452

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human CCD-841CoN cells incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type CCD-841CoN
Confidence 1 — Organism
Curated By Autocuration

Target

CCD-841CoN (CHEMBL4296406)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of Cytotoxic Nitric Oxide-Releasing Piperlongumine Derivatives Targeting Wnt/β-Catenin in Colon Cancer Cells.
Zou Y, He Y, Tan L, Xu X, Qi C, Zhang Y.
J Nat Prod (2024) 87 : 1893 -1902
PubMed 39045852 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.95 4.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5589752 1 4.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5589752 IC50 = 11300.0 nM 4.95