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Assay Detail

CHEMBL5587774

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNA-PK (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA-dependent protein kinase catalytic subunit (CHEMBL3142)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small Molecular Inhibitors That Target ATM for Drug Discovery: Current Research and Potential Prospective.
Qian C, Li X, Zhang J, Wang Y.
J Med Chem (2024) 67 : 14742 -14767
PubMed 39149790 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5596626 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5596626 IC50 = 5.0 nM 8.30