Assay Detail
Functional
CHEMBL5587779
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Antiplasmodial activity against drug-resistant Plasmodium falciparum Dd2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure and Biosynthesis of Perochalasins A-C, Open-Chain Merocytochalasans Produced by the Marine-Derived Fungus <i>Peroneutypa</i> sp. M16.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.16 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5590158 | — | — | 1 | 5.16 |
| CHEMBL36 | PYRIMETHAMINE | 4.0 | 1 | - |
| CHEMBL1487 | ATORVASTATIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5590158 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL36 | PYRIMETHAMINE | IC50 | > | 10000.0 | nM | - |
| CHEMBL1487 | ATORVASTATIN | IC50 | - | — | - |