Assay Detail
Binding
CHEMBL5588909
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Inhibition of MAO-A (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.93 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3906257 | — | — | 1 | 6.29 |
| CHEMBL5596377 | — | — | 1 | 5.81 |
| CHEMBL5591195 | — | — | 1 | 5.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3906257 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL5596377 | — | IC50 | = | 1540.0 | nM | 5.81 |
| CHEMBL5591195 | — | IC50 | = | 2050.0 | nM | 5.69 |