Assay Detail
Binding
CHEMBL5608440
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Inhibition of PDE1 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.59 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572409 | — | — | 1 | 7.40 |
| CHEMBL3769414 | LENRISPODUN | 2.0 | 1 | 7.30 |
| CHEMBL1628659 | — | — | 1 | 7.16 |
| CHEMBL190 | THEOPHYLLINE ANHYDROUS | 4.0 | 1 | 6.55 |
| CHEMBL71752 | VINPOCETINE | 2.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572409 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3769414 | LENRISPODUN | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL1628659 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL190 | THEOPHYLLINE ANHYDROUS | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL71752 | VINPOCETINE | IC50 | = | 30000.0 | nM | 4.52 |