Assay Detail
Binding
CHEMBL5608445
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE3A (unknown origin) using FAM-cAMP as substrate incubated for 45 mins by TR-FRET analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (CHEMBL241) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.57 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL799 | CILOSTAZOL | 4.0 | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL799 | CILOSTAZOL | IC50 | = | 27.0 | nM | 7.57 |