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Assay Detail

CHEMBL5608464

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of TTBK2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tau-tubulin kinase 2 (CHEMBL3337327)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Current therapy in amyotrophic lateral sclerosis (ALS): A review on past and future therapeutic strategies.
Wei Y, Zhong S, Yang H, Wang X, Lv B, Bian Y, Pei Y, Xu C, Zhao Q, Wu Y, Luo D, Wang F, Sun H, Chen Y.
Eur J Med Chem (2024) 272 : 116496 -116496
PubMed 38759454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.80 8.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5193906 1 8.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5193906 IC50 = 1.6 nM 8.80