Assay Detail

CHEMBL5608656

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Functional

Antiproliferative activity against human K562 cells

ChEMBL ↗

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Target

K562 (CHEMBL385) ↗

Open DB target context

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Primary target K562

CHEMBL385

Anchored from Assay target.

Protein identity K562

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	K562
Confidence	1 — Organism
Curated By	Autocuration

Target

K562 (CHEMBL385) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Structural modification strategies of triazoles in anticancer drug development.

Guan Q, Gao Z, Chen Y, Guo C, Chen Y, Sun H.
Eur J Med Chem (2024) 275 : 116578 -116578
PubMed 38889607 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.08	6.08

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4778826	—	—	1	6.08

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4778826	—	IC50	=	840.0	nM	6.08