Assay Detail
Binding
CHEMBL5611096
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PRMT1 (unknown origin) by scintillation proximity assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein arginine N-methyltransferase 1 (CHEMBL5524) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure, Function, and Activity of Small Molecule and Peptide Inhibitors of Protein Arginine Methyltransferase 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559689 | — | — | 1 | 8.52 |
| CHEMBL5612531 | — | — | 1 | 8.52 |
| CHEMBL3901808 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559689 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL5612531 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL3901808 | — | IC50 | = | 30000.0 | nM | - |