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Assay Detail

CHEMBL5614564

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PI3K (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Pan Y, Hou H, Zhou B, Gao J, Gao F.
Eur J Med Chem (2023) 262 : 115879 -115879
PubMed 37875056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.06 8.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4536105 1 8.09
CHEMBL5618885 1 8.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4536105 IC50 = 8.1 nM 8.09
CHEMBL5618885 IC50 = 9.3 nM 8.03