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Assay Detail

CHEMBL5614575

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human U-937 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent viability assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U-937
Confidence 1 — Organism
Curated By Autocuration

Target

U-937 (CHEMBL612794)
Type CELL-LINE
Organism Homo sapiens

Publication

Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Pan Y, Hou H, Zhou B, Gao J, Gao F.
Eur J Med Chem (2023) 262 : 115879 -115879
PubMed 37875056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5618885 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5618885 IC50 = 0.3 nM 9.52