Assay Detail
Functional
CHEMBL5614620
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against mouse A20 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | A20 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.17 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4536105 | — | — | 1 | 7.64 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4536105 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 199.0 | nM | 6.70 |