Assay Detail
Binding
CHEMBL5614671
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild type BRAF (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase B-raf (CHEMBL5145) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.77 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5618301 | — | — | 1 | 8.77 |
| CHEMBL5618517 | — | — | 1 | 8.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5618301 | — | IC50 | = | 1.71 | nM | 8.77 |
| CHEMBL5618517 | — | IC50 | = | 1.71 | nM | 8.77 |