Assay Detail
Functional
CHEMBL5614712
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Antiproliferative activity against human HeLa cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.87 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4639966 | — | — | 1 | 7.30 |
| CHEMBL5180137 | — | — | 1 | 5.16 |
| CHEMBL5618265 | — | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4639966 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5180137 | — | IC50 | = | 6910.0 | nM | 5.16 |
| CHEMBL5618265 | — | IC50 | = | 7010.0 | nM | 5.15 |