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Assay Detail

CHEMBL5614792

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against Plasmodium falciparum 3D7 assessed as reduction in parasite growth incubated for 3 days by ELISA analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency.
Pan Y, Hou H, Zhou B, Gao J, Gao F.
Eur J Med Chem (2023) 262 : 115879 -115879
PubMed 37875056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.72 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5620086 1 8.72
CHEMBL5619232 1 8.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5620086 IC50 = 1.9 nM 8.72
CHEMBL5619232 IC50 = 1.9 nM 8.72