Assay Detail
Binding
CHEMBL5614871
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Binding affinity to DNA (unknown origin) assessed as DNA intercalation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Quinazolines annelated at the N(3)-C(4) bond: Synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.40 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 4.50 |
| CHEMBL5619378 | — | — | 1 | 4.37 |
| CHEMBL5619817 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 31270.0 | nM | 4.50 |
| CHEMBL5619378 | — | IC50 | = | 42900.0 | nM | 4.37 |
| CHEMBL5619817 | — | IC50 | = | 48130.0 | nM | 4.32 |