Assay Detail
Functional
CHEMBL5615281
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Antiviral activity against Human rhinovirus 86 infected in human H1-HeLa cells assessed as reduction in cytopathic effect incubated for 72 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus B86 |
| Cell Type | H1-HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.38 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5618151 | — | — | 1 | 8.22 |
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 7.05 |
| CHEMBL5619521 | — | — | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5618151 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL283403 | ENVIROXIME | EC50 | = | 89.0 | nM | 7.05 |
| CHEMBL5619521 | — | EC50 | = | 139.0 | nM | 6.86 |