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Assay Detail

CHEMBL5615852

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to GABAA receptor (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

GABA-A receptor; anion channel (CHEMBL2093872)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.
Bai YR, Yang X, Chen KT, Cuan XD, Zhang YD, Zhou L, Yang L, Liu HM, Yuan S.
Eur J Med Chem (2024) 277 : 116759 -116759
PubMed 39137454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.10 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1568698 GANAXOLONE 4.0 1 6.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1568698 GANAXOLONE Ki = 790.0 nM 6.10